Physicians need to recommend individuals in the possible for VIAGRA to reinforce the hypertension decreasing result of alpha-blockers and anti-hypertensive medicines. Concomitant administration of VIAGRA and an alpha-blocker may bring on symptomatic hypotension in a few people.
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Safety of combined use of PDE5 inhibitors and alpha-blockers might be impacted by other variables, which includes intravascular volume depletion and also other anti-hypertensive drugs.
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VIAGRA was demonstrated to potentiate the hypotensive effects of nitrates and its administration in sufferers who use nitric oxide donors which include organic nitrates or organic and natural nitrites in almost any type is for that reason contraindicated [see CONTRAINDICATIONS, DRUG INTERACTIONS, and Scientific PHARMACOLOGY].
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